Melatonin

Futurist and anti-aging writer Ray Kurzweil gobbles down 250 supplements per day. To us normal folk such measures seem excessive given the limited power of such interventions. At the other extreme, contemporaries like Aubrey de Grey see little value in supplements.

Often the truth lies somewhere in the middle. Supplementation won’t extend your lifetime but there is a good chance it can improve the quality of your life. After all, who wants to hang on to a miserable existence with a frail body? What we really need is a way to maintain our vitality and our youthful approach to living.

1. Resveratrol

There isn’t a more promising compound within the grasp of mere mortals. The scientific studies and evidence behind resveratrol continues to stack up. Findings have been largely positive although major pharmaceutical companies have funded unfavourable studies of questionable credibility.

Resveratrol mimics the effects of caloric restriction, which to date is the only known way to slow down the effects of age-related disease in mammals. As a side effect of the way it alters metabolism, resveratrol fends off the threat of type 2 diabetes. This means that overweight people benefit from it more than thin, active people.